Oncology Pipeline
Loxo@Lilly aims to create medicines that make life better for all those affected by cancer around the world. Bringing together the focus and spirit of a biotech with the scale, resources, and heritage of Lilly, our team is focused on rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating oncology medicines that unequivocally show early signs of clinical activity and will matter to patients.
FGFR3 Inhibitor
LOXO-435

Repetto M, et al1; Chen L, et al2
Target
Molecule
Clinical Development
References
- Repetto M, et al. Expert Rev Clin Pharmacol. 2021;14(10):1233-1252.
- Chen L, et al. J Exp Clin Cancer Res. 2021;40(1):345.
- Krook MA, et al. Br J Cancer. 2021;124(5):880-892.
- Katoh M. Nat Rev Clin Oncol. 2019;16(2):105-122.
- Glaser AP, et al. Nat Rev Urol. 2017;14(4):215-229.
- Helsten T, et al. Clin Cancer Res. 2016;22(1):259-267.
- Ballard JA, et al. Mol Cancer Ther. 2021;20(12_Suppl):P141.
- Haugsten EM, et al. Mol Cancer Res. 2010;8(11):1439-1452.
- Loriot Y, et al. N Engl J Med. 2019;381(4):338-348.
Need additional information or have a question:
The safety and efficacy of the agents under investigation have not been established. There is no guarantee that the agents will receive regulatory approval and become commercially available for the uses being investigated.