Oncology Pipeline

For more than 50 years, Lilly has been dedicated to delivering life-changing medicines and support to people living with cancer and those who care for them. Lilly is determined to build on this heritage and continue making life better for all those affected by cancer around the world. In 2019 Lilly created Loxo Oncology at Lilly, with the goal of rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating new medicines that work in early clinical development and will matter to patients.

Neuroblastoma
LY3295668
CLL/SLL
BTK Inhibitor Enrolling
Pirtobrutinib, LOXO-305
CLL/SLL or NHL
BTK Inhibitor Enrolling
Pirtobrutinib, LOXO-305
MCL
BTK Inhibitor Enrolling
Pirtobrutinib, LOXO-305
Breast Cancer
Abemaciclib, LY2835219
Pediatric Cancer
Abemaciclib, LY2835219
Prostate Cancer
Abemaciclib, LY2835219
Prostate Cancer
Abemaciclib, LY2835219
Advanced Hematologic Malignancies
IDH1 Inhibitor Enrolling
LY3410738
Advanced Solid Tumors
IDH1 Inhibitor Enrolling
LY3410738
Colorectal Cancer, NSCLC, or Other Advanced Solid Tumors
LY3537982
Medullary Thyroid Cancer
RET Inhibitor Enrolling
Selpercatinib, LOXO-292, LY3527723
NSCLC
RET Inhibitor Enrolling
Selpercatinib, LOXO-292, LY3527723
NSCLC
RET Inhibitor Enrolling
Selpercatinib, LOXO-292, LY3527723
NSCLC, Medullary Thyroid Cancer, Papillary Thyroid Carcinoma, or Other Advanced Solid Tumors
RET Inhibitor Enrolling
Selpercatinib, LOXO-292, LY3527723
Pediatric Cancer
RET Inhibitor Enrolling
Selpercatinib, LOXO-292, LY3527723
Breast Cancer or Endometrial Cancer
Imlunestrant, LY3484356
Breast Cancer
Imlunestrant, LY3484356
Pediatric Cancer
Ramucirumab, LY3009806, IMC‑1121B
Pediatric Cancer
Ramucirumab, LY3009806, IMC‑1121B