Oncology Pipeline
For more than 50 years, Lilly has been dedicated to delivering life-changing medicines and support to people living with cancer and those who care for them. Lilly is determined to build on this heritage and continue making life better for all those affected by cancer around the world. In 2019 Lilly created Loxo Oncology at Lilly, with the goal of rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating new medicines that work in early clinical development and will matter to patients.
CD73 Inhibitor
LY3475070

Allard D, et al1; Leone RD and Emens LA2; Leone RD, et al3; Young A, et al4; Fishman P, et al5
Target
Molecule
Clinical Development
References
- Allard D, et al. Immunol Lett. 2019;205:31-39.
- Leone RD, Emens LA. J Immunother Cancer. 2018;6(1):57.
- Leone RD, et al. Comput Struct Biotechnol J. 2018;13:265-272.
- Young A, et al. Cancer Discov. 2014;4(8):879-888.
- Fishman P, et al. Handb Exp Pharmacol. 2009;(193):399-441.
- Brahmer JR, Pardoll DM. Cancer Immunol Res. 2013;1(2):85-91.
- Horenstein AL, et al. Front Immunol. 2019;10:760.
- Zhang B. Cancer Res. 2010;70(16):6407-6411.
- Robeva AS, et al. Biochem Pharmacol. 1996;51(4):545-555.
The safety and efficacy of the agents under investigation have not been established. There is no guarantee that the agents will receive regulatory approval and become commercially available for the uses being investigated.